Asymmetric Intramolecular Carbocyanation of Unsaturated Olefins via C-C Bond Activation**
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چکیده
Every organic functional group coordinates with each transition metal in a characteristic manner. Upon coordination, the reactivity of these functional groups is often dramatically altered. In this way the normal reactivity patterns of functional groups can be inverted, and unconventional transformations can be achieved with facility. Most organometallic reactions are highly specific, able to discriminate between structurally similar sites, thus avoiding the standard protection-deprotection sequences. Transition metal complexes containing metal-carbon σ-bonds are intermediates to a majority of transformations leading to the formation of carboncarbon bonds (with identical or different hybridization), which are of supreme importance in organic synthesis.
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تاریخ انتشار 2009